General description

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates that paromomycin binding to the A-site of 16S rRNA induces a local conformational change, suggesting a mechanism for aminoglycoside action on protein translation. Also exhibits anti-protozoal properties.

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates paromomycin binding to the A-site of 16S rRNA induces a local conformational change that suggests a mechanism for aminoglycoside action on protein translation.

Potency: ≥675 µg/mg.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

VanLoock, M.S., et al. 1999. J. Mol. Biol. 285, 2069.Blanchard, S.C., et al. 1998. Biochemistry 37, 7716.Fourmy, D., et al. 1998. J. Mol. Biol. 277, 333.

Packaging

5 g in Glass bottle

Warning

Toxicity: Harmful (C)